Know more

Our use of cookies

Cookies are a set of data stored on a user’s device when the user browses a web site. The data is in a file containing an ID number, the name of the server which deposited it and, in some cases, an expiry date. We use cookies to record information about your visit, language of preference, and other parameters on the site in order to optimise your next visit and make the site even more useful to you.

To improve your experience, we use cookies to store certain browsing information and provide secure navigation, and to collect statistics with a view to improve the site’s features. For a complete list of the cookies we use, download “Ghostery”, a free plug-in for browsers which can detect, and, in some cases, block cookies.

Ghostery is available here for free:

You can also visit the CNIL web site for instructions on how to configure your browser to manage cookie storage on your device.

In the case of third-party advertising cookies, you can also visit the following site:, offered by digital advertising professionals within the European Digital Advertising Alliance (EDAA). From the site, you can deny or accept the cookies used by advertising professionals who are members.

It is also possible to block certain third-party cookies directly via publishers:

Cookie type

Means of blocking

Analytical and performance cookies

Google Analytics

Targeted advertising cookies


The following types of cookies may be used on our websites:

Mandatory cookies

Functional cookies

Social media and advertising cookies

These cookies are needed to ensure the proper functioning of the site and cannot be disabled. They help ensure a secure connection and the basic availability of our website.

These cookies allow us to analyse site use in order to measure and optimise performance. They allow us to store your sign-in information and display the different components of our website in a more coherent way.

These cookies are used by advertising agencies such as Google and by social media sites such as LinkedIn and Facebook. Among other things, they allow pages to be shared on social media, the posting of comments, and the publication (on our site or elsewhere) of ads that reflect your centres of interest.

Our EZPublish content management system (CMS) uses CAS and PHP session cookies and the New Relic cookie for monitoring purposes (IP, response times).

These cookies are deleted at the end of the browsing session (when you log off or close your browser window)

Our EZPublish content management system (CMS) uses the XiTi cookie to measure traffic. Our service provider is AT Internet. This company stores data (IPs, date and time of access, length of the visit and pages viewed) for six months.

Our EZPublish content management system (CMS) does not use this type of cookie.

For more information about the cookies we use, contact INRA’s Data Protection Officer by email at or by post at:

24, chemin de Borde Rouge –Auzeville – CS52627
31326 Castanet Tolosan CEDEX - France

Dernière mise à jour : Mai 2018

Menu Logo Principal Agrocampus Ouest

ESE - Ecology and Ecosystem Health

Comparative population genomics in animals and plants: genetic diversity, selection efficacy and effective population size

ESEminar 2019-05-14
Sylvain Glémin, UMR ECOBIO, CNRS Rennes, will lead the next ESEminaire

When? Tuesday 14 May 2019, at 13:00

Where? Roux Amphitheatre, Building 15, Agrocampus Ouest


What determines levels of genetic diversity within species is a central question in evolutionary biology but has remained a puzzling question for decades. Particularly the relative influences of species biology and ecology versus population history have been much debated. To address this question we investigated the genome-wide diversity of 76 non-model animal species by sequencing the transcriptome of two to ten individuals  in each species. The distribution of synonymous genetic diversity (πS)  between species revealed no detectable influence of geographic range or  invasive status but was accurately predicted by key species traits related to parental investment: long-lived or low-fecundity species with  brooding ability were genetically less diverse than short-lived or highly fecund ones. Then we extended this analysis to a comparison with plants by analysing full-genome data in 34 animal and 28 plant species.
As in animals, we found a strong effect of longevity and, in addition, of mating systems. We then tested whether the efficacy of purifying selection was affected by the effective size of a population (Ne). In agreement with the nearly neutral theory of molecular evolution, we found a strong negative correlation between πS (as a proxy for Ne) and πNS, the ratio of non-synonymous vs synonymous diversity (as a proxy for the efficacy of purifying selection). In addition, we also found that the distribution of fitness effect of mutations also varies among species, contributing to variation in πNS
Finally I will present results on the specific effect of mating systems  on genetic diversity and the efficacy of selection at a much smaller phylogenetic scale, focusing on wheat relatives. From these results, I will discuss how global life-history strategies can affect Ne and the efficacy of selection and whether genomic-based measures, such as πNS, can tell us something about the fate of a species.