Know more

Our use of cookies

Cookies are a set of data stored on a user’s device when the user browses a web site. The data is in a file containing an ID number, the name of the server which deposited it and, in some cases, an expiry date. We use cookies to record information about your visit, language of preference, and other parameters on the site in order to optimise your next visit and make the site even more useful to you.

To improve your experience, we use cookies to store certain browsing information and provide secure navigation, and to collect statistics with a view to improve the site’s features. For a complete list of the cookies we use, download “Ghostery”, a free plug-in for browsers which can detect, and, in some cases, block cookies.

Ghostery is available here for free: https://www.ghostery.com/fr/products/

You can also visit the CNIL web site for instructions on how to configure your browser to manage cookie storage on your device.

In the case of third-party advertising cookies, you can also visit the following site: http://www.youronlinechoices.com/fr/controler-ses-cookies/, offered by digital advertising professionals within the European Digital Advertising Alliance (EDAA). From the site, you can deny or accept the cookies used by advertising professionals who are members.

It is also possible to block certain third-party cookies directly via publishers:

Cookie type

Means of blocking

Analytical and performance cookies

Realytics
Google Analytics
Spoteffects
Optimizely

Targeted advertising cookies

DoubleClick
Mediarithmics

The following types of cookies may be used on our websites:

Mandatory cookies

Functional cookies

Social media and advertising cookies

These cookies are needed to ensure the proper functioning of the site and cannot be disabled. They help ensure a secure connection and the basic availability of our website.

These cookies allow us to analyse site use in order to measure and optimise performance. They allow us to store your sign-in information and display the different components of our website in a more coherent way.

These cookies are used by advertising agencies such as Google and by social media sites such as LinkedIn and Facebook. Among other things, they allow pages to be shared on social media, the posting of comments, and the publication (on our site or elsewhere) of ads that reflect your centres of interest.

Our EZPublish content management system (CMS) uses CAS and PHP session cookies and the New Relic cookie for monitoring purposes (IP, response times).

These cookies are deleted at the end of the browsing session (when you log off or close your browser window)

Our EZPublish content management system (CMS) uses the XiTi cookie to measure traffic. Our service provider is AT Internet. This company stores data (IPs, date and time of access, length of the visit and pages viewed) for six months.

Our EZPublish content management system (CMS) does not use this type of cookie.

For more information about the cookies we use, contact INRA’s Data Protection Officer by email at cil-dpo@inra.fr or by post at:

INRA
24, chemin de Borde Rouge –Auzeville – CS52627
31326 Castanet Tolosan CEDEX - France

Dernière mise à jour : Mai 2018

Menu Logo Principal Agrocampus Ouest Rennes 1 University

Home page

Tagu Denis

Tagu Denis
Team: Ecology and Genetics of Insects

Phone: (+33) 2 23 48 51 65
Denis.Tagu@inra.fr
Senior Scientist, INRA

UMR 1349 IGEPP, BP 35327 - 35653 Le Rheu Cedex - France

Tel: (+33) 2 23 48 51 65

Tel: (+33) 6 76 35 67 93

e-mail: denis.tagu@inra.fr

Education and Professional Experience

  • INRA Senior Scientist position, Insect genomics and phenotypic plasticity, Rennes, France (2002-today)
  • Sabbatical, CRG (Barcelona, Spain), August 2017-January 2018
  • INRA Junior Scientist position, Plant-Fungal symbiotic interactions, Nancy, France (1991-2002)
  • Post-doc fellowship (European Union), Plant Molecular Genetics, CSIC, Barcelona, Spain (1989-1991)
  • PhD Plant Molecular Physiology, Orsay-Paris University, France (1985-1988)

Ongoing projects

Management

  • International Aphid Genomics Consortium (www.aphidbase.com)
  • Associate Editor Insect Science
  • Member of the i5K coordinating group (http://arthropodgenomes.org/wiki/i5K)
  • Member of the GIGA consortium (http://giga-cos.org/)
  • Coordination of 4 insect genome sequencing (http://www.spe.inra.fr/Toutes-les-actualites/i5k-sequencer-5000-genomes-d-insectes)
  • Coordination of ANR project on association genetics in the pea aphid (2012-2014)
  • Coordination of ANR project on microRNAs and gene network in the pea aphid (2009-2012)
  • Coordination of ANR project on genes responsible for sex determination in aphids (2018-2020)
  • Partner of the European Training Network IGNITE on invertebrate genomics (2018-2022)
  • Head of the Institute of Genetics, Environment and Plant Protection: more than 260 persons involved in describing, understanding and modeling agroecosystems, plants and their pathogens, pests and auxiliaries (2012-2016)
  • Associate Editor BMC Genomics
  • Associate Editor Current Opinion Insect Science

Areas of Focus

  • Genomics
  • Integrative genomics
  • Bioinformatics
  • Insect adaptation
  • Phenotypic plasticity

Selected publications (July 2017 - h index: 31 – citations: 2848)

Genome and genome-derived papers

The International Aphid Genomics Consortium, Tagu D., Legeai F., Gauthier J.P., Rispe C., Ollivier M. & Jaubert-Possamai S. (2010). Genome sequence of the pea aphid Acyrthosiphon pisum. PLoS Biology 8(2):e1000313. DOI

Rispe C, Kutsukake M, Doublet V, Hudaverdian S, Legeai F, Simon JC, Tagu D, Fukatsu T (2008) Large gene family expansion and variable selective pressures for cathepsin B in aphids. Molecular Biology and Evolution 25:5-17. DOI

Jaubert-Possamai S., Rispe C., Tanguy S., Gordon K., Walsh T., Edwards O. & Tagu D. (2010). Expansion of the miRNA pathway in the hemipteran insect Acyrthosiphon pisum. Molecular Biology and Evolution 27(5):979-987. DOI

Walsh T.K., Brisson J.A., Robertson H.M., Gordon K., Jaubert-Possamai S., Tagu D. & Edwards O.R. (2010). A functional DNA methylation system in the pea aphid, Acyrthosiphon pisum. Insect Molecular Biology 19(s2):215-228. DOI

Carolan J.C., Caragea D., Reardon K.T., Mutti N.S., Dittmer N., Pappan K., Cui F., Castaneto M., Poulain J., Dossat C., Tagu D., Reese J.C., Reeck G.R., Wilkinson T.L. & Edwards O.R. (2011). Predicted Effector Molecules in the Salivary Secretome of the Pea Aphid (Acyrthosiphon pisum): A Dual Transcriptomic/Proteomic Approach. Journal of Proteome Research 10(4):1505-1518. DOI

Lu H.-l., Tanguy S., Rispe C., Gauthier J.-P., Walsh T., Gordon K., Edwards O., Tagu D., Chang C.-c. & Jaubert-Possamai S. (2011). Expansion of Genes Encoding piRNA-Associated Argonaute Proteins in the Pea Aphid: Diversification of Expression Profiles in Different Plastic Morphs. PLoS ONE 6(12):e28051. DOI

Ollivier M., Gabaldón T., Poulain J., Gavory F., Leterme N., Gauthier J.-P., Legeai F., Tagu D., Simon J.C. & Rispe C. (2012). Comparison of gene repertoires and patterns of evolutionary rates in eight aphid species that differ by reproductive mode. Genome Biology and Evolution 19(2):33-45. DOI

Ortiz-Rivas B, Jaubert-Possamai1 S, Tanguy S, Gauthier JP, Tagu D, Rispe C. (2012) Evolutionary study of duplications of the miRNA machinery in aphids associated with striking rate acceleration and changes in expression profiles. BMC Evolutionary Biology, 12:216. DOI

i5k consortium (Hackett et al. dont Tagu D). The i5K Initiative: Advancing Arthropod Genomics for Knowledge, Human Health, Agriculture, and the Environment (2013). Journal of Heredity 104 595-600. DOI

Tagu D., Colbourne J.K., & Nègre N. (2014). Genomic data integration for ecological and evolutionary traits in non-model organisms. BMC genomics 15: 490. DOI

Rispe C, Legeai F, Papura D, Bretaudeau A, Hudaverdian S, Le Trionnaire G, Tagu D, Jaquiéry J & Delmotte F (2016) De novo assembly of the grapevine phylloxera transcriptome allows identification of genes differentially expressed between leaf- and root-feeding forms. BMC Genomics 17: 219. DOI

Mathers TC, et al., including Tagu D. (2017) Rapid transcriptional plasticity of duplicated gene clusters enables a clonally reproducing aphid to colonise diverse plant species. Genome Biology 18, 27. DOI

Phenotypic plasticity

Le Trionnaire G, Jaubert S, Sabater-Muñoz B, Benedetto A, Bonhomme J, Prunier-Leterme N, Martinez-Torres D, Simon JC, Tagu D (2007) Seasonal photoperiodism regulates the expression of cuticular and signalling protein genes in the pea aphid. Insect Biochemistry and Molecular Biology 37 1094-1102. DOI

Rispe C, Legeai F, Gauthier JP, Tagu D (2007) Strong heterogeneity in nucleotidic composition and codon bias in the pea aphid (Acyrthosiphon pisum) shown by EST-Based coding genome reconstruction. Journal of Molecular Evolution 65:413-424. DOI

Le Trionnaire G, Francis F, Jaubert S, Bonhomme J, De Pauw E, Gauthier JP, Haubruge E, Legeai F, Prunier-Leterme N, Simon JC, Tanguy S, Tagu D (2009) Transcriptomic and proteomic analyses of seasonal photoperiodism in the pea aphid. BMC Genomics, 10(456):14. DOI

Huybrechts H, Bonhomme J, Minoli S, Prunier-Leterme N, Dombrovsky A, Abdel-Latief M, Robichon A, Veenstra JA, Tagu D (2010) Neuropeptide and neurohormone precursors in the pea aphid Acyrthosiphon pisum. Insect Molecular Biology, 19(s2):87-95. DOI

Legeai F., Risk G., Walsh T., Edwards O., Gordon K., Lavenier D., Leterme N., Méreau A., Nicolas J., Tagu D. & Jaubert-Possamai S. (2010). Bioinformatic prediction, deep sequencing of microRNAs and their role in phenotypic plasticity in the pea aphid, Acyrthosiphon pisum. BMC Genomics 11:281. DOI

Gallot A., Shigenobu S., Hashiyama T., Jaubert-Possamai S. & Tagu D. (2012). Sexual and asexual oogenesis require the expression of unique and shared sets of genes in the insect Acyrthosiphon pisum. Bmc genomics 13(1):76. DOI

Ishikawa A., Ogawa K., Gotoh H., Walsh T.K., Tagu D., Brisson J.A., Rispe C., Jaubert-Possamai S., Kanbe T., Tsubota T., Shiotsuki T. & Miura T. (2012). Juvenile hormone titre and related gene expression during the change of reproductive modes in the pea aphid. Insect Molecular Biology 21(1):49-60. DOI

Le Trionnaire G.,  Jaubert-Possamai S., Bonhomme J., Gauthier J.P., Guernec G., Le Cam A., Montfort J. Legeai F., Tagu D. (2012). Transcriptomic profiling of the reproductive mode switch in the pea aphid Acyrthosiphon pisum in response to natural autumnal photoperiod. Journal of Insect Physiology, 58 1517-1524. DOI

Jaquiéry J, Rispe C, Roze D, Legeai F, Le Trionnaire G, Stoeckel S, Mieuzet L, Da Silva C, Poulain J, Prunier-Leterme N, Ségurens B, Tagu D & Simon JC. (2013). Masculinization of the X chromosome in the pea aphid. PLoS Genetics vol 9 e1003690. DOI

Jaquiéry J., Stoeckel S., Larose C., Nouhaud P., Rispe C., Mieuzet L., Bonhomme J., Mahéo F., Legeai F., Gauthier J.P., Prunier-Leterme N., Tagu D. & Simon J.C. (2014). Genetic Control of Contagious Asexuality in the Pea Aphid. PLoS Genetics, 10(12): e1004838. DOI

Richard G, Legeai F, Prunier-Leterme N, Bretaudeau A, Tagu D, Jaquiery Julie, Le Trionnaire G. (2017) Dosage compensation and sex-specific epigenetic landscape of the X chromosome in the pea aphid. Epigenetics and Chromatin, 10, 30. DOI

Tools and resources

Sabater-Muñoz B, Legeai F, Rispe C, Bonhomme J, Dearden P, Dossat C, Duclert A, Gauthier JP, Ducray DG, Hunter W, Dang P, Kambhampati S, Martinez-Torres D, Cortes T, Moya A, Nakabachi A, Philippe C, Prunier-Leterme N, Rahbe Y, Simon JC, Stern DL, Wincker P, Tagu D (2006) Large-scale gene discovery in the pea aphid Acyrthosiphonpisum (Hemiptera). Genome Biology 7. DOI

Jaubert-Possamai S, Le Trionnaire G, Bonhomme J, Christophides GK, Rispe C, Tagu D (2007) Gene knockdown by RNAi in the pea aphid Acyrthosiphon pisum. BMC Biotechnology 7. DOI

Legeai F., Shigenobu S., Gauthier J.P., Colbourne J., Rispe C., Collin O., Richards S., Wilson A.C.C., Murphy T. & Tagu D. (2010). AphidBase: a centralized bioinformatic resource for annotation of the pea aphid genome. Insect Molecular Biology 19(s2):5-12. DOI

Tagu D., Le Trionnaire G., Tanguy S., Gauthier J.P. & Huynh J.R. (2014). EMS Mutagenesis in the Pea Aphid Acyrthosiphon pisum. G3: Genes|Genomes|Genetics, 4: 657-667. DOI

Wucher V., Tagu D., Nicolas J. (2015). Edge Selection in a Noisy Graph by Concept Analysis: Application to a Genomic Network ; Studies in Classification, Data Analysis, and Knowledge Organization In Springer. In press

Reviews and book chapters

Le Trionnaire G, Hardie J, Jaubert-Possamai S, Simon JC, Tagu D (2008) Shifting from clonal to sexual reproduction in aphids: physiological and developmental aspects. Biology of the Cell 100:441-451. DOI

Tagu D, Klingler JP, Moya A, Simon JC (2008) Early progress in aphid genomics and consequences for plant-aphid interactions studies. Molecular Plant-Microbe Interactions 21:701-708. DOI

Gallot-Le Grand A., Rispe C., Leterme N., Gauthier J.P., Jaubert-Possamai S. & Tagu D. (2010). Cuticular proteins and seasonal photoperiodism in aphid. Insect Biochemistry and Molecular Biology 40(3):235-240. DOI

Simon J.C., Stoeckel S. & Tagu D. (2010). Evolutionary and functional insights into reproductive strategies of aphids. Comptes Rendus Biologies 333(6-7):488-496. DOI

Tagu D., Dugravot S., Outreman Y., Rispe C., Simon J.C. & Colella S. (2010). The anatomy of an aphid genome: from sequence to biology. Comptes Rendus Biologies 333(6-7):464-473. DOI

Simon J.C., Pfrender M.E., Tollrian R., Tagu D. & Colbourne J.K. (2011). Genomics of Environmentally Induced Phenotypes in 2 Extremely Plastic Arthropods. Journal of Heredity 102(5):512-525. DOI

Le Trionnaire G, Wucher V, Tagu D (2013) Genome expression control during the photoperiodic response of aphids. Physiological Entomology (2013) 38, 117–125. DOI

Tagu D., Colbourne J.K., &Nègre N. (2014). Genomic data integration for ecological and evolutionary traits in non-model organisms. BMC genomics 15: 490. DOI

Editorial : Coste F. & Tagu D. (2012). 13e journées ouvertes en biologie, informatique et mathématiques. JOBIM 2012 (Rennes, France).

Editorial : Brisson J.A. & Tagu D. (2014). Editorial overview: Insect genomics. Current Opinion in Insect Science, 1: v-vi.

Editorial : Brown S.J. & Tagu D. (2015). Editorial overview: Insect genomics: How to sequence five thousand insect genomes? Current Opinion in Insect Science, 7: iv-v.

Grantham M., Brisson J.A., Tagu D. & Le Trionnaire G. (Accepted) Integrative Genomic Approaches to Studying Epigenetic Mechanisms of Phenotypic Plasticity in the Aphid. In C. Raman, M. R. Goldsmith & T. Agunbiade (Eds.), Short Views on Insect Genomics and Proteomics - Insect Genomics: Springer. Book Series: Entomology in Focus Volume: 3 Pages: 95-117. DOI

Brisson J.A., Jaquiéry J., Legeai F., Le Trionnaire G. & Tagu D. (2017). Genomics of phenotypic plasticity in aphids. In H. Czosnek & M. Ghanim (Eds.), Management of insect pests to agriculture: lessons learned from deciphering their genome, transcriptome and proteome: Springer 65-96. DOI

Tagu D., Calevro F., Colella S., Gabaldon T. & Sugio A. (Accepted). Functional and evolutionary genomics in aphids. In A. Vilcinskas (Ed.), Biology & Ecology of Aphids: CRC Press 52-88.

Loxdale H.D., Edwards D., Tagu D. & Vorburger C. Population Genetic Issues: New Insights Using Conventional Molecular Markers and Genomics Tools. In H. F. van Emden & R. Harrington (Eds.), Aphids as Crop Pests: CABI Press. In press

Books (Editor) (in french)

Tagu D, Moussard C (2003) Principes des techniques de biologie moléculaire. 2nde edition. INRA Editions 176 pages

Book translated in English (2006), Spanish (2006) anf Chinese (2007)

Tagu D. & Risler J.L. (2010) Bio-informatique : principes d'utilisation des outils (Quae).

Selected invited presentations at international conferences

2012 XXIV International Congress of Entomology (Daegu, South- Korea)

2012 6th annual arthropod genomics symposium (Kansas City, USA)

2013 10th Gordon Conference “Ecology and Evolutionary Genomics” (New England, USA)

2013 Entomological Society of America’s Annual Meeting (Austin, USA)

2013 6th International Symposium on Phylloxera, (Bordeaux, France)

2014 7th International Symposium on Molecular Insect Science, (Amsterdam, Pays-Bas)

2014 4th International Conference on Diabrotica Genetics, (Chicago, USA)

2014 TGAC workshop on “regulatory elements in non-model organisms”, (Norwich, UK)

2015 2nd Global Invertebrate Genomics Alliance Workshop, (München, Allemagne)

2015 CRG (Barcelone, Espagne)

2016 International Conference on Entomolgy, (Orlando, Florica, USA)

Organization of international conferences

7th International Symposium on Molecular Insect Science Amsterdam 2014, scientific committee

IAGC (6 workshops, with the last on planned for 25th sept 2016 at Orlando, Florida, USA

Entomological Society of America’s Annual Meeting  (organization of microRNA symposium)

International Conference on Entomology (Orlando 2016) (organization of epigenetics symposium)